Unai Emery rotated his squad for the midweek clash with Vitoria Guimaraes in the Europa League.
Only Joe Willock started from the side that lost the Premier League clash with Sheffield United on Monday night – a game in which Willock had been hooked at half-time.
Arsenal failed to impress against the Portuguese side, only claiming victory thanks to two late free kicks from substitute Nicolas Pepe.
As such, expect changes again today against Crystal Palace; Arsenal fans may be hoping for starts for both Hector Bellerin and Kieran Tierney, after both recently returned from injury, but this may be a step too soon given they both played the full 90 on Thursday night.
Thus, it seems likely that both Sead Kolasinac and Calum Chambers will retain their places in the full-back berths.
Dani Ceballos should start however, replacing Willock, while Pepe – buoyed by those two goals – will also start in attack.
Bukayo Saka will drop to the bench, with Alexandre Lacazette preferred and thus leading the line.
That will mean top scorer Pierre-Emerick Aubameyang operating from the left.
Mesut Ozil was again absent from the squad in midweek, and some Arsenal fans took to chanting his name.
However, at a time where a section of fans appear to be running out of patience with Emery and his methods, Bellerin insists the Gunners squad are very much behind their manager.
“This team has evolved a lot since the beginning of last season,” says the fit-again Spaniard.
“When the board sign a manager like Unai, they know it’s all part of a process.
“He has his own ideas – and he’s done so well at Sevilla, Valencia and Paris Saint-Germain that everyone trusts in the manager.”
Arsenal predicted lineup: Leno; Chambers, Sokratis, Luiz, Kolasinac; Xhaka, Guendouzi, Ceballos; Pepe, Lacazette, Aubameyang.